HARARE, Oct 19 (Reuters) - Zimbabwean Prime Minister Morgan Tsvangirai will meet regional leaders this week to put pressure on coalition partner President Robert Mugabe to settle disputes in the unity government, a senior aide said on Monday.

Tsvangirai said on Friday his Movement for Democratic Change (MDC) party would disengage from Mugabe's "dishonest and unreliable" ZANU-PF party in the unity cabinet set up in February.

Political analysts say the MDC's decision may not mean the end of the power-sharing government but it will put pressure on the Southern African Development Community (SADC), the regional body under whose auspices former South African President Thabo Mbeki brokered a settlement in Zimbabwe last year.

The MDC boycott has created the country's most serious political crisis since the formation of the new administration. Mugabe's spokesman George Charamba said on Sunday Mugabe would chair a cabinet meeting on Tuesday without the MDC.

The SADC said Tsvangirai would meet Mozambican President Armando Guebuza, who chairs the SADC's political panel on defence and security, on Tuesday in Mozambique.